Proteomics

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Comparative proteomics in schistosoma japonicum


ABSTRACT: In this study, isobaric tags for relative and absolute quantification (iTRAQ) were used to identify differential expression proteins (DEPs) of adult schistosomes across two different intermediate host development: Oncomelania hupensis (O.hupensis) and Oncomelania weishan (O.weishan).

ORGANISM(S): Schistosomatidae Sp. W829 Schistosomatidae Sp. W688

SUBMITTER: Gongzhen Liu  

PROVIDER: PXD035090 | iProX | Mon Oct 24 00:00:00 BST 2022

REPOSITORIES: iProX

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Comparative proteomics analysis of <i>Schistosoma japonicum</i> developed in different <i>Oncomelania</i> snails as intermediate hosts.

Liu Gongzhen G   Miao Feng F   Wang Yongbin Y   Kou Jingxuan J   Yang Kun K   Li Wei W   Xiong Chunrong C   Zhang Fengjian F   Wang Xinyao X   Yan Haoyun H   Wei Changyin C   Zhao Changlei C   Yan Ge G  

Frontiers in cellular and infection microbiology 20221101


Schistosomiasis is a tropical parasitic disease that seriously endangers humans and animals. In this study, two <i>Oncomelania</i> snails, <i>Oncomelania hupensis</i> (<i>O. hupensis</i>) and <i>Oncomelania weishan</i> (<i>O. weishan</i>), were infected with <i>Schistosoma japonicum</i> (<i>S. japonicum</i>) cercariae during the early period, and ICR mice were subsequently infected with two kinds of miracidia that developed in male and female adult worms. In this study, isobaric tags for relativ  ...[more]

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