Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: Wei Ge
PROVIDER: PXD035096 | iProX | Wed Jul 06 00:00:00 BST 2022
REPOSITORIES: iProX
Frontiers in oncology 20220722
Previous studies have shown that the presence of perineural invasion (PNI) is associated with a significantly worse prognosis in colorectal cancer (CRC) patients. In this study, we performed a detailed analysis of the diversity of extracellular vesicles (EV) between NPNI (non-PNI) and PNI using quantitative proteomics and aim to investigate the mechanisms underlying PNI in colorectal cancer. Quantitative proteomics technology was used to identify the proteome of serum-purified EVs from CRC patie ...[more]