Proteomics detection of mouse embryonic 17.5 dpc cultured ovaries in vitro

ABSTRACT: In this project, the ovaries of mice at 17.5 dpc embryonic stage were collected, and KN93, an inhibitor of CAMKII, and IWP2, an inhibitor of Wnt5a, were added for in vitro culture. Proteins affected by KN93 and IWP2, which were regulated by CAMKII and Wnt5a, were detected by proteomics technology, so as to identify the target proteins regulated by CAMKII and Wnt5a. To analyze the possible mechanisms of CAMKII and Wnt5a on the development of primordia follicles in mouse ovaries. 

ORGANISM(S): Mus Musculus

SUBMITTER: Guoliang Xia  

PROVIDER: PXD035136 | iProX | Thu Jul 07 00:00:00 BST 2022

REPOSITORIES: iProX