Guo Yi Y Li Jinli J Hao Fengdan F Yang Yang Y Yang Hao H Chang Qiurong Q Kong Pengcheng P Liu Wenqiang W Jiao Xianting X Teng Xiaoming X
Frontiers in endocrinology 20230104
<h4>Background</h4>Semen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive. Sperm proteins or semen metabolites are used as the intermediate or end-products, reflecting changes in semen quality, and hold much promise as a new biomarker to predict fertility in advanced-aged males.<h4>Objectives</h4>In this study, we sought to assess whether the semen metabolome and proteome of aged males can affect semen qual ...[more]