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Proteome in mouse brain infected by zika virus

ABSTRACT: The proteomic data of ZIKV-infected mice at 14 dpi were obtained by mass spectrometry, and we observed 68 differentially expressed proteins between infected and control mice

ORGANISM(S): Mus Musculus

SUBMITTER: Aiping Wu

PROVIDER: PXD035467 | iProX | Mon Jul 04 00:00:00 BST 2022

REPOSITORIES: iProX

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Immune profiles in mouse brain and testes infected by Zika virus with variable pathogenicity.

Shang Jingzhe J Li Chunfeng C Jin Zhujia Z Zu Shulong S Chen Songjie S Chen Junlan J Chen Ziyi Z Tang Hua H Qin Cheng-Feng CF Ye Qing Q Wu Aiping A

Frontiers in cellular and infection microbiology 20220804

The Zika virus is responsible for neurological diseases such as microcephaly, Guillain-Barré syndrome, neuropathy, and myelitis in human adults and children. Previous studies have shown that the Zika virus can infect nerve progenitor cells and interfere with neural development. However, it is unclear how the immune system responds to infection with Zika viruses with variable pathogenicity. Here, we used two Zika strains with relatively different pathogenicity, the Asian ancestral strain CAM/2010 ...[more]

PMID: 35992167

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