The data of protein expression of hMSCs in Soft, Medium and Stiff group
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Jialin Chen
PROVIDER: PXD035511 | iProX | Thu Jul 21 00:00:00 BST 2022
REPOSITORIES: iProX
Publications
Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells.
Sheng Renwang R Liu Jia J Zhang Wei W Luo Yifan Y Chen Zhixuan Z Chi Jiayu J Mo Qingyun Q Wang Mingyue M Sun Yuzhi Y Liu Chuanquan C Zhang Yanan Y Zhu Yue Y Kuang Baian B Yan Chunguang C Liu Haoyang H Backman Ludvig J LJ Chen Jialin J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20230425 17
Stiffness is an important physical property of biomaterials that determines stem cell fate. Guiding stem cell differentiation via stiffness modulation has been considered in tissue engineering. However, the mechanism by which material stiffness regulates stem cell differentiation into the tendon lineage remains controversial. Increasing evidence demonstrates that immune cells interact with implanted biomaterials and regulate stem cell behaviors via paracrine signaling; however, the role of this ...[more]
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