Silica-exposed BEAS-2B epithelial cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Jin Chen
PROVIDER: PXD035608 | iProX | Thu Jul 28 00:00:00 BST 2022
REPOSITORIES: iProX
Publications
Profiling of metabolites, proteins, and protein phosphorylation in silica-exposed BEAS-2B epithelial cells.
Chen Jin J Wang Hanshi H Gao Hongzhi H Zeng Yiming Y
PloS one 20230411 4
Silicosis is an uncurable occupational disease induced by crystalline silica. Increased prevalence of silicosis has resulted in the increased need for development of treatment options. Although macrophages respond first to silica, epithelial cells are also involved in silicosis. However, changes in protein and metabolite levels have not been reported simultaneously. We used mass spectrometry to profile changes in metabolites, proteins, and phosphorylation in silica-exposed BEAS-2B epithelial cel ...[more]
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