A Rapid and Sensitive Single-cell Proteomic Method Based on Fast LC Separation, Deep-learning RT Prediction and MS1-only Acquisition

ABSTRACT: We report an integrate strategy that combines fast liquid chromatography (LC) separation, deep learning-based retention time (RT) prediction and MS1-only acquisition for sensitive and rapid single-cell proteome analysis. Finally, SCP-MS1 was applied to sorafenib resistant HepG2 cells.

ORGANISM(S): Homo Sapiens

SUBMITTER: Weijie Qin  

PROVIDER: PXD036211 | iProX | Fri Aug 26 00:00:00 BST 2022

REPOSITORIES: iProX