ANXA1 promotes tumor immune evasion by binding PARP1 and upregulating the transcription of PD-L1 in the multiple cancers

ABSTRACT: To search proteins that interact with ANXA1, ANXA1 interactors were coimmunoprecipitated with anti-ANXA1 antibody from MB231 cell extracts, separated on SDS-PAGE and stained with Coomassie blue , and non-immune IgG antibody instead of anti-ANXA1 antibody served as control. All bands were excised, and subjected to in gel trypsin digestion and liquid chromatography and high-throughput mass spectrometry (LC-MS/MS) analysis.As a result, a total of 489 proteins including PARP1 were identified .

ORGANISM(S): Homo Sapiens

SUBMITTER: Zhiqiang Xiao  

PROVIDER: PXD036235 | iProX | Tue Aug 23 00:00:00 GMT+01:00 2022

REPOSITORIES: iProX