Proteomics

Dataset Information

0

DIA-based proteomic analysis of CHD patients with PBS Syndrome

ABSTRACT: We conducted a DIA-based proteomics study for 5 patients with CHD-PBS Syndrome, 5 patients with CHD-NPBS Syndrome, and 5 healthy adults to explore the biomarkers of PBS Syndrome.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jie Wang  

PROVIDER: PXD036389 | iProX | Tue Aug 30 00:00:00 BST 2022

REPOSITORIES: iProX

Json Xml
altmetric image

Publications

Exploring the "gene-protein-metabolite" network of coronary heart disease with phlegm and blood stasis syndrome by integrated multi-omics strategy.

Yang Guang G   Zhou Siyuan S   He Haoqiang H   Shen Zinuo Z   Liu Yongmei Y   Hu Jun J   Wang Jie J  

Frontiers in pharmacology 20221129

<b>Background:</b> According to the theory of traditional Chinese medicine, phlegm and blood stasis (PBS) is the pathological basis for coronary heart disease (CHD). This study aimed to explore the biological basis of PBS syndrome in CHD. <b>Methods:</b> Using a strategy that integrated RNA-seq, DIA-based proteomics, and untargeted metabolomics on 90 clinic samples, we constructed a "gene-protein-metabolite" network for CHD-PBS syndrome. We expanded the sample size and validated the differential  ...[more]

Similar Datasets

Unknown Genomewide methylation analysis in Silver Russell syndrome patients
2015-01-12 | GSE55491 | GEO
Transcriptomics PBMCs from patients with Sjögren's syndrome and healthy controls
2013-09-05 | E-GEOD-48378 | biostudies-arrayexpress
Transcriptomics Genomewide methylation analysis in Silver Russell syndrome patients
2015-01-12 | E-GEOD-55491 | biostudies-arrayexpress
Unknown PBMCs from patients with Sjögren's syndrome and healthy controls
2013-09-05 | GSE48378 | GEO
Unknown DNA methylation of fibroblasts from Cockayne syndrome and UV-sensitivity syndrome patients [EPIC]
2023-12-24 | GSE163840 | GEO
Unknown DNA methylation of fibroblasts from Cockayne syndrome and UV-sensitivity syndrome patients [450k]
2023-12-24 | GSE163839 | GEO
no omics defined Transcription profiling of lymphoblastoid cell lines isolated from healthy and Aicardi Syndrome patients
2007-01-01 | E-MEXP-725 | biostudies-arrayexpress
Genomics Elstera litoralis strain:Dia-1
| PRJNA278930 | ENA
Genomics scRNAseq RAT DIA WT and DMD 12months
| PRJNA814255 | ENA
Genomics Transcriptomic profiling of VEXAS syndrome patients
| PRJNA672843 | ENA