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The proteomics of IgG4-related disease and healthy controls

ABSTRACT: Proteomic characteristics of saliva and plasma in patients of IgG4-RD and healthy controls.

ORGANISM(S): Homo Sapiens

SUBMITTER: Lingli Dong

PROVIDER: PXD036552 | iProX | Wed Sep 07 00:00:00 BST 2022

REPOSITORIES: iProX

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Proteomic characteristics of saliva in patients with different subgroups of IgG4-RD.

Lin Sheng-Yan SY Zhou Tianshu T Cai Shaozhe S Hu Zi-Wei ZW Zhong Jixin J Dong Lingli L

Frontiers in immunology 20221122

<h4>Background</h4>Immunoglobulin G4-related disease (IgG4-RD) is a newly defined disease entity, with great heterogeneity among IgG4-RD subgroups with different organ involvement patterns. Identification of the proteomic characteristics of IgG4-RD subgroups will be critical for the understanding of the pathogenic mechanisms of IgG4-RD.<h4>Method</h4>In this study, we performed proteomic analysis using Tandem Mass Tags (TMT) technology with "high field" mass analyzer with improved resolution and ...[more]

PMID: 36483554

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