Proteomics

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Label-Free proteomic analysis and functional analysis in patients with intrauterine adhesion


ABSTRACT: Intrauterine adhesion is a common disease in women of childbearing age. In recent years, due to the increasing number of uterine operations, the incidence has been increasing, resulting in rising rate of secondary infertility in women. At present, the mechanism of intrauterine adhesion is still unclear, and there are few reports on proteomics.

ORGANISM(S): Homo Sapiens

SUBMITTER: Yong Li  

PROVIDER: PXD036768 | iProX | Fri Sep 16 00:00:00 BST 2022

REPOSITORIES: iProX

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Publications

Label-free proteomic analysis and functional analysis in patients with intrauterine adhesion.

Ye Jingxuan J   Li Yong Y   Kong Chengcai C   Ren Yiwen Y   Lu Hangcheng H  

Journal of proteomics 20230224


Intrauterine adhesion (IUA) is one of the principal causes of secondary infertility in women of reproductive age, which seriously affects female reproductive function and quality of life. In recent years, the incidence of IUA has been increasing year by year, but its pathological mechanism has not yet been clarified. This study intended to reveal the pathogenesis of IUA and find new therapeutic targets by analyzing the proteomic differences between intrauterine adhesion tissues and normal human  ...[more]

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