The in-depth plasma proteomics of Diffuse large B-cell lymphoma
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Yuankai Shi
PROVIDER: PXD036842 | iProX | Fri Jun 09 00:00:00 BST 2023
REPOSITORIES: iProX
Publications
Proteomics Identifies Circulating TIMP-1 as a Prognostic Biomarker for Diffuse Large B-Cell Lymphoma.
Lou Ning N Wang Guibin G Wang Yanrong Y Xu Meng M Zhou Yu Y Tan Qiaoyun Q Zhong Qiaofeng Q Zhang Lei L Zhang Xiaomei X Liu Shuxia S Luo Rongrong R Wang Shasha S Tang Le L Yao Jiarui J Zhang Zhishang Z Shi Yuankai Y Yu Xiaobo X Han Xiaohong X
Molecular & cellular proteomics : MCP 20230726 9
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease, although disease stratification using in-depth plasma proteomics has not been performed to date. By measuring more than 1000 proteins in the plasma of 147 DLBCL patients using data-independent acquisition mass spectrometry and antibody array, DLBCL patients were classified into four proteomic subtypes (PS-I-IV). Patients with the PS-IV subtype and worst prognosis had increased levels of proteins involved in inflammation, including ...[more]
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