Dataset Information
Candida albicans NDT80 Family protein Rep1 mass spectrometry
Ontology highlight
ABSTRACT:
ORGANISM(S): Candida Albicans Cas15
SUBMITTER: 
Yang Lu
PROVIDER: PXD037522 | iProX | Tue Oct 18 00:00:00 BST 2022
REPOSITORIES: iProX
Publications
Recognition of galactose by a scaffold protein recruits a transcriptional activator for the <i>GAL</i> regulon induction in <i>Candida albicans</i>.
eLife 20230201
The <i>GAL</i> pathway of yeasts has long served as a model system for understanding of how regulatory mode of eukaryotic metabolic pathways evolves. While Gal4 mode has been well-characterized in Saccharomycetaceae clade, little is known about the regulation of the <i>GAL</i> pathway in other yeasts. Here, we find that Rep1, a Ndt80-like family transcription factor, serves as a galactose sensor in the commensal-pathogenic fungus <i>Candida albicans</i>. It is presented at the <i>GAL</i> gene pr ...[more]
