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The DIA analysis of renal tissue

ABSTRACT: The mouse model of septic kidney injury was established by cecal ligation, and the kidney tissue was obtained 12 hours later. The kidney tissue between CLP group and control group was analyzed by mass spectrometry.

ORGANISM(S): Mus <genus>

SUBMITTER: Xinjin Chi

PROVIDER: PXD037640 | iProX | Fri Oct 21 00:00:00 BST 2022

REPOSITORIES: iProX

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CTSB promotes sepsis-induced acute kidney injury through activating mitochondrial apoptosis pathway.

Wang Yuting Y Xi Wenjie W Zhang Xinyi X Bi Xinwen X Liu Boyang B Zheng Xiaoming X Chi Xinjin X

Frontiers in immunology 20230113

<h4>Background</h4>Acute kidney injury is a common and severe complication of sepsis. Sepsis -induced acute kidney injury(S-AKI) is an independent risk factor for mortality among sepsis patients. However, the mechanisms of S-AKI are complex and poorly understand. Therefore, exploring the underlying mechanisms of S-AKI may lead to the development of therapeutic targets.<h4>Method</h4>A model of S-AKI was established in male C57BL/6 mice using cecal ligation and puncture (CLP). The data-independen ...[more]

PMID: 36713420

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