Ontology highlight
ABSTRACT:
ORGANISM(S): Mus <genus>
SUBMITTER: Tiannan Guo
PROVIDER: PXD037950 | iProX | Fri Nov 04 00:00:00 GMT 2022
REPOSITORIES: iProX
Li Lu L Sun Cuiji C Sun Yaoting Y Dong Zhen Z Wu Runxin R Sun Xiaoting X Zhang Hanbin H Jiang Wenhao W Zhou Yan Y Cen Xufeng X Cai Shang S Xia Hongguang H Zhu Yi Y Guo Tiannan T Piatkevich Kiryl D KD
Nature communications 20221130 1
Spatially resolved proteomics is an emerging approach for mapping proteome heterogeneity of biological samples, however, it remains technically challenging due to the complexity of the tissue microsampling techniques and mass spectrometry analysis of nanoscale specimen volumes. Here, we describe a spatially resolved proteomics method based on the combination of tissue expansion with mass spectrometry-based proteomics, which we call Expansion Proteomics (ProteomEx). ProteomEx enables quantitative ...[more]