Proteomics

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Proteomic study of Toxoplasma gondii infection in cibeaver


ABSTRACT: Proteomics in South China Agricultural University essentially refers to the study of protein characteristics at a large-scale level, including protein expression level, post-translational modification, protein-protein interaction and so on, so as to obtain an overall and comprehensive understanding of disease occurrence, cell metabolism and other processes at the protein level.

ORGANISM(S): Paguma Larvata

SUBMITTER: Hao Yuan  

PROVIDER: PXD038083 | iProX | Wed Nov 09 00:00:00 GMT 2022

REPOSITORIES: iProX

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Publications

Multiomics and bioinformatics identify differentially expressed effectors in the brain of <i>Toxoplasma gondii</i> infected masked palm civet.

Yuan Hao H   Jiang Tiantian T   Zhang Wei-Dong WD   Yang Zipeng Z   Luo Shengjun S   Wang Xiaohu X   Zhu Xiaojing X   Qi Shuting S   Mahmmod Yasser S YS   Zhang Xiu-Xiang XX   Yuan Zi-Guo ZG  

Frontiers in cellular and infection microbiology 20230925


<h4>Introduction</h4>The masked palm civet (<i>Paguma larvata</i>) serves as a reservoir in transmitting pathogens, such as <i>Toxoplasma gondii</i>, to humans. However, the pathogenesis of <i>T. gondii</i> infection in masked palm civets has not been explored. We studied the molecular changes in the brain tissue of masked palm civets chronically infected with <i>T. gondii</i> ME49.<h4>Methods</h4>The differentially expressed proteins in the brain tissue were investigated using iTRAQ and bioinfo  ...[more]

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