Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: Jusheng Zheng
PROVIDER: PXD038253 | iProX | Tue Nov 22 00:00:00 GMT 2022
REPOSITORIES: iProX
Xu Fengzhe F Yu Evan Yi-Wen EY Cai Xue X Yue Liang L Jing Li-Peng LP Liang Xinxiu X Fu Yuanqing Y Miao Zelei Z Yang Min M Shuai Menglei M Gou Wanglong W Xiao Congmei C Xue Zhangzhi Z Xie Yuting Y Li Sainan S Lu Sha S Shi Meiqi M Wang Xuhong X Hu Wensheng W Langenberg Claudia C Yang Jian J Chen Yu-Ming YM Guo Tiannan T Zheng Ju-Sheng JS
Nature communications 20230216 1
Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic evidence needs to be generalizable to diverse populations. Given that the majority of the previous studies were conducted in European ancestry populations, little is known about the protein-associated genetic variants in East Asians. Based on data-independent acquisition m ...[more]