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Proteomics Analysis in Pediatric Viral Encephalitis and Meningitis

ABSTRACT: Proteomics Analysis in Pediatric Viral Encephalitis and Meningitis

ORGANISM(S): Homo Sapiens

SUBMITTER: Feng Gao

PROVIDER: PXD038291 | iProX | Wed Nov 23 00:00:00 GMT 2022

REPOSITORIES: iProX

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Metagenomic next-generation sequencing and proteomics analysis in pediatric viral encephalitis and meningitis.

Wang Yi-Long YL Guo Xiao-Tong XT Zhu Meng-Ying MY Mao Yu-Chen YC Xu Xue-Bin XB Hua Yi Y Xu Lu L Jiang Li-Hua LH Zhao Cong-Ying CY Zhang Xin X Sheng Guo-Xia GX Jiang Pei-Fang PF Yuan Zhe-Feng ZF Gao Feng F

Frontiers in cellular and infection microbiology 20230421

<h4>Introduction</h4>Early and accurate identification of pathogens is essential for improved outcomes in patients with viral encephalitis (VE) and/or viral meningitis (VM).<h4>Methods</h4>In our research, Metagenomic next-generation sequencing (mNGS) which can identify viral pathogens unbiasedly was performed on RNA and DNA to identify potential pathogens in cerebrospinal fluid (CSF) samples from 50 pediatric patients with suspected VEs and/or VMs. Then we performed proteomics analysis on the 1 ...[more]

PMID: 37153144

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