IL-33 stabilizes the transcription factor IRF1

ABSTRACT: Interleukin-33 (IL-33) functions both as a secreted cytokine and as a nuclear factor, with pleiotropic roles in tumor growth and immunity. Here, we explored its role in hepatocellular carcinoma (HCC) and identified that its nuclear function mediated a mechanism of immune escape.

ORGANISM(S): Homo Sapiens

SUBMITTER: Zengbin Wang  

PROVIDER: PXD039110 | iProX | Wed Dec 28 00:00:00 GMT 2022

REPOSITORIES: iProX