Proteomics Landscape of Diverse Serological Patterns in COVID-19
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Tiannan Guo
PROVIDER: PXD039722 | iProX | Fri Jan 27 00:00:00 GMT 2023
REPOSITORIES: iProX
Publications
Proteomics Investigation of Diverse Serological Patterns in COVID-19.
Liang Xiao X Sun Rui R Wang Jing J Zhou Kai K Li Jun J Chen Shiyong S Lyu Mengge M Li Sainan S Xue Zhangzhi Z Shi Yingqiu Y Xie Yuting Y Zhang Qiushi Q Yi Xiao X Pan Juan J Wang Donglian D Xu Jiaqin J Zhu Hongguo H Zhu Guangjun G Zhu Jiansheng J Zhu Yi Y Zheng Yufen Y Shen Bo B Guo Tiannan T
Molecular & cellular proteomics : MCP 20230105 2
Serum antibodies IgM and IgG are elevated during Coronavirus Disease 2019 (COVID-19) to defend against viral attacks. Atypical results such as negative and abnormally high antibody expression were frequently observed whereas the underlying molecular mechanisms are elusive. In our cohort of 144 COVID-19 patients, 3.5% were both IgM and IgG negative, whereas 29.2% remained only IgM negative. The remaining patients exhibited positive IgM and IgG expression, with 9.3% of them exhibiting over 20-fold ...[more]
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