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Human neutrophil proteomics in the presence of pyroptotic macrophage-derived MVs

ABSTRACT: we isolated neutrophil from human blood, and then treatment with normal macrophage-derived MVs and pyroptotic macrophage-derived MVs. After 4h, the protein from these neutrophils was analysized by proteomics

ORGANISM(S): Homo Sapiens

SUBMITTER: Xi Huang

PROVIDER: PXD039812 | iProX | Thu Feb 02 00:00:00 GMT 2023

REPOSITORIES: iProX

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Distinct Mitochondria-Mediated T-Cell Apoptosis Responses in Children and Adults With Coronavirus Disease 2019.

Yang Yang Y Kuang Liangjian L Li Linhai L Wu Yongjian Y Zhong Bei B Huang Xi X

The Journal of infectious diseases 20211001 8

<h4>Background</h4>Lymphopenia is a key feature for adult patients with coronavirus disease 2019 (COVID-19), although it is rarely observed in children. The underlying mechanism remains unclear.<h4>Methods</h4>Immunohistochemical and flow cytometric analyses were used to compare the apoptotic rate of T cells from COVID-19 adults and children and apoptotic responses of adult and child T cells to COVID-19 pooled plasma. Biological properties of caspases and reactive oxygen species were assessed in ...[more]

PMID: 34374752

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