Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus Norvegicus
SUBMITTER: Jingxue Zhang
PROVIDER: PXD039972 | iProX | Thu Feb 09 00:00:00 GMT 2023
REPOSITORIES: iProX
Lin Danting D Wu Shen S Cheng Ying Y Yan Xuejing X Liu Qian Q Ren Tianmin T Zhang Jingxue J Wang Ningli N
Molecular & cellular proteomics : MCP 20231002 11
The pathogenesis of glaucoma is still unknown. There are few studies on the dynamic change of tissue-specific and time-specific molecular pathophysiology caused by ocular hypertension (OHT). This study aimed to identify the early proteomic alterations in the retina, optic nerve head (ONH), and optic nerve (ON). After establishing a rat model of OHT, we harvested the tissues from control and glaucomatous eyes and analyzed the changes in protein expression using a multiplexed quantitative proteomi ...[more]