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SWATH-MS-Based Proteomics of Amaryllidaceae Alkaloids in Lycoris Species

ABSTRACT: We determined the alkaloid content in Lycoris longituba, Lycoris incarnata, and Lycoris sprengeri, and performed a SWATH-MS-based quantitative approach to detect proteome changes in the three Lycoris.

ORGANISM(S): Amaryllidaceae

SUBMITTER: Qingzhu Li

PROVIDER: PXD040341 | iProX | Thu Feb 23 00:00:00 GMT 2023

REPOSITORIES: iProX

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SWATH-MS-Based Proteomics Reveals the Regulatory Metabolism of Amaryllidaceae Alkaloids in Three <i>Lycoris</i> Species.

Tang Meng M Li Chaohan C Zhang Cheng C Cai Youming Y Zhang Yongchun Y Yang Liuyan L Chen Moxian M Zhu Fuyuan F Li Qingzhu Q Li Kehu K

International journal of molecular sciences 20230224 5

Alkaloids are a class of nitrogen-containing alkaline organic compounds found in nature, with significant biological activity, and are also important active ingredients in Chinese herbal medicine. Amaryllidaceae plants are rich in alkaloids, among which galanthamine, lycorine, and lycoramine are representative. Since the difficulty and high cost of synthesizing alkaloids have been the major obstacles in industrial production, particularly the molecular mechanism underlying alkaloid biosynthesis ...[more]

PMID: 36901927

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