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LncRNA MAGI2-AS3-encoded polypeptide restrains the proliferation and migration of breast cancer cells

ABSTRACT: This study was conducted by using Flag tag to IP proteins expressed with fusion small peptides encoding LncRNA MAGI2-AS3 and identified by high resolution mass spectrometry.

ORGANISM(S): Homo Sapiens

SUBMITTER: Zhiwei Zhang

PROVIDER: PXD040607 | iProX | Mon Mar 06 00:00:00 GMT 2023

REPOSITORIES: iProX

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LncRNA MAGI2-AS3-Encoded Polypeptide Restrains the Proliferation and Migration of Breast Cancer Cells.

Zhang Zhiwei Z Yi Yanli Y Wang Zai Z Zhang Haoyun H Zhao Yanchun Y He Ruijing R Luo Yan Y Cui Zhiqiang Z

Molecular biotechnology 20230626 6

Accumulating articles have reported the coding potential of long non-coding RNAs (lncRNAs). However, only a few lncRNAs-encoded peptides have been studied. Breast cancer (BRCA) progression-related gene modules were determined by weighted gene co-expression network analysis (WGCNA). Cell viability, proliferation, and migration capacities were assessed by Cell counting kit-8 (CCK8), 5-ethynyl-2'-deoxyuridine (EdU), and transwell assays. Immunofluorescence (IF) assay was implemented to observe prot ...[more]

PMID: 37358745

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