Proteomic Profiling of Serum Exosomes in Patients with Heat Stroke
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Zhengtao Gu
PROVIDER: PXD040640 | iProX | Mon Mar 06 00:00:00 GMT 2023
REPOSITORIES: iProX
Publications
Proteomic profiling of serum exosomes reveals acute phase response and promotion of inflammatory and platelet activation pathways in patients with heat stroke.
Li Yue Y Li Huan H Ma Wenjuan W Maegele Marc M Tang Youqing Y Gu Zhengtao Z
PeerJ 20231213
<b>Background:</b> The pathological mechanism of heat stroke (HS) involves the acute phase response, unbalanced immunological/inflammatory reactions, and coagulation initiation, especially platelet activation. Although exosomes contain proteins involved in these biological processes, their protein cargo levels and potential roles in HS remain unknown. This study explored the serum exosome protein expression patterns after HS and their potential roles in the pathogenesis of HS. <b>Methods:</b> Bl ...[more]
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