(−)-Vinigrol Targets PDI-ADAM17 Module to Induce TNFR1 Shedding and Ameliorate Rheumatoid Arthritis in Mice

ABSTRACT: Our study indicates that targeting the PDI-ADAM17 signaling module to regulate the shedding of cytokine receptors by the chemical approach constitutes a novel strategy for alleviating RA

ORGANISM(S): Mus Musculus

SUBMITTER: Tuoping Luo  

PROVIDER: PXD040753 | iProX | Fri Mar 10 00:00:00 GMT 2023

REPOSITORIES: iProX