Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway

ABSTRACT: The purpose of this study is to investigate the therapeutic effect of MSC-derived apoVs treatment on NIHL and the potential mechanism of resisting oxidative stress damage in hair cells, as well as the distribution of apoptotic vesicles in the inner ear. The study provided a new direction for the treatment of noise-induced hearing loss and inner ear delivery.

ORGANISM(S): Homo Sapiens

SUBMITTER: Haidi Yang  

PROVIDER: PXD040989 | iProX | Mon Mar 20 00:00:00 GMT 2023

REPOSITORIES: iProX