Dataset Information
Proteomic and phenotypic studies of Mycoplasma pneumoniae revealed macrolide resistant mutation (A2063G) associated changes in protein composition and pathogenicity of type I strains
Ontology highlight
ABSTRACT:
ORGANISM(S): Mycoplasma Pneumoniae
SUBMITTER: 
Deli Xin
PROVIDER: PXD041114 | iProX | Fri Mar 24 00:00:00 GMT 2023
REPOSITORIES: iProX
Publications
Proteomic and Phenotypic Studies of Mycoplasma pneumoniae Revealed Macrolide-Resistant Mutation (A2063G) Associated Changes in Protein Composition and Pathogenicity of Type I Strains.
Microbiology spectrum 20230628 4
Mycoplasma pneumoniae (MP) is an important respiratory pathogen, the prevalence of macrolide-resistant MP (mainly containing A2063G mutation in 23S rRNA) increased in recent years. Epidemiological studies suggest a higher prevalence of type I resistant (IR) strains than corresponding sensitive (IS/IIS) strains, but not type II resistant (IIR) strains. Here, we aimed to analyze the factors underlying the altered prevalence of IR strains. First, proteomic analyses exhibit the protein compositions ...[more]
