Proteomics

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Quantitative proteomic analysis of changes in the proteome of UTP18-knockdown colorectal cancer cells


ABSTRACT: The protein UTP18 was consistently upregulated in the normal-adenoma-carcinoma sequence. In vitro experiments showed that knockdown of UTP18 suppressed proliferation, invasion, and migration of colorectal cancer cells, as well as inhibited tumorigenicity in nude mice. To investigate the regulatory mechanism of UTP18 on the phenotype of colorectal cancer cells, we performed quantitative proteomic analysis on CRC cells with UTP18 knockdown.

ORGANISM(S): Homo Sapiens

SUBMITTER: Wei Ge  

PROVIDER: PXD041150 | iProX | Tue Mar 28 00:00:00 BST 2023

REPOSITORIES: iProX

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