Caspase-2 is a condensate-mediated deubiquitinase in protein quality control

ABSTRACT: When cells encounter proteome stresses, caspase-2 accumulates in a ubiquitin-rich condensate, which functions as a deubiquitinase to cleave the overloaded ubiquitinated proteins.

ORGANISM(S): Homo Sapiens

SUBMITTER: Lingqiang Zhang  

PROVIDER: PXD041964 | iProX | Wed Sep 06 00:00:00 BST 2023

REPOSITORIES: iProX