Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The Study of Chinese Medicine Intervention on Apoptosis of Cochlear hair cells in C57BL/6J Aged Cochlea

ABSTRACT: Through the intervention of traditional Chinese medicine prescription on cochlear hair cell apoptosis of c57 mice to 7-month-old mice, the proteomic analysis of cochlear hair cell apoptosis of 7-month-old mice and 2-month-old mice in the non traditional Chinese medicine group was compared to try to find the target or related pathway of Chinese medicine affecting cochlear senile apoptosis.

ORGANISM(S): Mus Musculus

SUBMITTER: Weijun Xuan

PROVIDER: PXD041998 | iProX | Thu May 04 00:00:00 BST 2023

REPOSITORIES: iProX

ACCESS DATA

Json Xml

Similar Datasets

traditional chinese medicine

Project description:traditional chinese medicine Targeted loci

| PRJNA796441 | ENA

Expression data from colon cancer cell HCT116 mouse xenograft - Control vs. traditional Chinese medicine Astragalus membranaceus-treated conditions

Project description:To identify biomarkers regulated by traditional Chinese medicine Astragalus membranaceus Fischer Bge. var. mongolicus Bge. Hsiao in colorectal cancer. We have identified several differentially expressed genes including microRNAs using Affymetrix HTA-2.0 array. In this dataset, we include the expression data obtained from colon cancer cell line HCT116 grafted into nude mice. The mice was treated either water or traditional Chinese medicine Astragalus membranaceus for 28 days. These data are used to obtain 1425 genes that are differentially expressed in response to Astragalus membranaceus treatment.

2017-02-13 | GSE70772 | GEO

Epigenetic profiling of H3K4me3 reveals Herbal Medicine Jinfukang-induced epigenetic alteration is involved in anti-Lung Cancer activity

Project description:Traditional Chinese medicine Jinfukang (JFK) has been used for lung cancer treatment for more than ten years, however, the mechanism is not well understood. Previously we showed that JFK inhibited survival of a human lung cell line A459 via cell apoptosis and inducing cell cycle arrest. To better understand the mechanism, we performed ChIP-seq assays to evaluate the effect of JFK on genome-wide profiling of H3K4Me3 modification.

2016-06-01 | E-MTAB-3992 | biostudies-arrayexpress

Differences in serum proteins in traditional Chinese medicine constitutional population: analysis and verification

Project description:Using high-throughput antibody microarray, through cross-sectional sample detection and verification of samples that had undergone physical changes over time, it was found that people with balanced constitution and dampness constitution in Chinese medicine showed differences in serum protein expression. The differences were expressed as the level changes of 19 proteins such as Dectin-2, Siglec-7, AIF and TACI. The research results provided the basis for the scientific expression of traditional Chinese medicine (TCM) constitution.

2019-11-22 | GSE140769 | GEO

Microbial sequencing of traditional Chinese medicine fermentation broth

Project description:Microbial sequencing of traditional Chinese medicine fermentation broth

| PRJEB35333 | ENA

Lianzhifan solution: a traditional Chinese medicine

Project description:Lianzhifan solution: a traditional Chinese medicine Raw sequence reads

| PRJNA556807 | ENA

Expression Profiling-based Clustering of Healthy Subjects Recapitulates Classifications Defined by Clinical Observation in Chinese Medicine

Project description:Based on the theory of constitution of Traditional Chinese Medicine (TCM), healthy individuals can be grouped into distinctive types. the global gene expression signature for distinctive constitutions has not been sufficiently explored. Here we examined gene expression profiles from 32 Chinese Han individuals with Yang/Yin deficiency (n=12 each) and Balanced constitutions (n=8).

2019-09-29 | GSE87474 | GEO

Transcriptomics of the traditional Japanese medicine juzentaihoto (JTX) on germfree mice

Project description:This SuperSeries is composed of the following subset Series: GSE32083: Transcriptomics of the traditional Japanese medicine juzentaihoto (JTX) on large intestines on germfree mice GSE32084: Transcriptomics of the traditional Japanese medicine juzentaihoto (JTX) on small intestines on germfree mice Refer to individual Series

2011-09-13 | E-GEOD-32085 | biostudies-arrayexpress

food metagenome

Project description:Traditional Chinese Medicine Metagenome

| PRJNA230360 | ENA

A network pharmacology study of Chinese Medicine QSYQ to reveal its underlying multi-compound, multi-target, multi-pathway mode of action

Project description:Chinese medicine is a complex system guided by traditional Chinese medicine (TCM) theories, which has proven to be especially effective in treating chronic and complex diseases. However, the underlying modes of action (MOA) are not always systematically investigated. Herein, a systematic study was designed to elucidate the multi-compound, multi-target and multi-pathway MOA of a Chinese medicine ,QSYQ, on myocardial infarction. Male Sprague Dawley rat model of myocardial infarction were administered QSYQ intragastrically for 7 days while the control group was not treated. The differentially expressed genes (DEGs) were identified from myocardial infarction rat model treated with QSYQ, followed by constructing a cardiovascular disease (CVD)-related multilevel compound-target-pathway network connecting main compounds to those DEGs supported by literature evidences and the pathways that are functionally enriched.

2014-01-17 | GSE54134 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data