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Potential Functionality of Cutibacterium acnes Extracellular Vesicles in Atopic Dermatitis and Acne Vulgaris: A Comparative Proteomic Analysis

ABSTRACT: Comparative analysis of Cutibacterium acnes extracellular vesicles proteomics from atopic dermatitis and acne vulgaris.

ORGANISM(S): Cutibacterium Acnes 6609

SUBMITTER: Ying Ma

PROVIDER: PXD042715 | iProX | Sat Jun 03 00:00:00 BST 2023

REPOSITORIES: iProX

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Potential functionality of Cutibacterium acnes extracellular vesicles in atopic dermatitis and acne vulgaris: A comparative proteomic analysis.

Yu Tianze T Chen Jin J Wu Shi S Jiang Min M Han Ling L Ma Ying Y

Proteomics. Clinical applications 20240419

<h4>Background</h4>Cutibacterium acnes is a commensal bacterium residing in healthy skin and plays a critical role in maintaining skin homeostasis. C. acnes has been considered closely related to acne vulgaris, while recent studies suggest that C. acnes and its metabolites may have a protective role in atopic dermatitis (AD) by modulating the immune system and maintaining skin homeostasis. Extracellular vesicles (EVs) are small membranous vesicles secreted by bacteria that participate in bacteri ...[more]

PMID: 38639920

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