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Phosphoproteomic and proteomic profiling in post-infarction chronic heart failure

ABSTRACT: We conducted a global quantitative phosphoproteomic and proteomic analysis of left ventricular (LV) tissues from post-infarction chronic heart failure rats. Phosphoproteomic and proteomic analysis can provide insights regarding molecular mechanisms underlying post-infarction chronic heart failure and explore new therapeutic approaches.

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Xiao Lu

PROVIDER: PXD042843 | iProX | Fri Jun 09 00:00:00 BST 2023

REPOSITORIES: iProX

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Phosphoproteomic and proteomic profiling in post-infarction chronic heart failure.

Wang Jiayue J Zhu Xiuhua X Wang Shenrui S Zhang Yingjie Y Hua Wenjie W Liu Zhenyu Z Zheng Yu Y Lu Xiao X

Frontiers in pharmacology 20230619

<b>Background:</b> Post-infarction chronic heart failure is the most common type of heart failure. Patients with chronic heart failure show elevated morbidity and mortality with limited evidence-based therapies. Phosphoproteomic and proteomic analysis can provide insights regarding molecular mechanisms underlying post-infarction chronic heart failure and explore new therapeutic approaches. <b>Methods and results:</b> Global quantitative phosphoproteomic and proteomic analysis of left ventricular ...[more]

PMID: 37405054

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