Targeting USP8 inhibits O-GlcNAcylation of SLC7A11 to promote ferroptosis of hepatocellular carcinoma via stabilization of OGT

ABSTRACT: To explore the proteins that are potentially regulated by USP8, we performed immunoprecipitation-based mass spectrometry (IP-MS) following ectopic expression of Flag-USP8 and immunoprecipitation. We noticed that the O-Linked N-Acetylglucosamine (GlcNAc) Transferase (OGT) was immunoprecipitated by USP8

ORGANISM(S): Homo Sapiens

SUBMITTER: Jianing Tang  

PROVIDER: PXD043781 | iProX | Mon Jul 10 00:00:00 BST 2023

REPOSITORIES: iProX