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Simultaneous deep transcriptome and proteome profiling in single mouse oocytes

ABSTRACT: Deep proteome data in the single-cell multi-omics analysis of single mouse oocytes.

ORGANISM(S): Mus Musculus

SUBMITTER: Qun Fang

PROVIDER: PXD043935 | iProX | Tue Oct 17 00:00:00 BST 2023

REPOSITORIES: iProX

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Simultaneous deep transcriptome and proteome profiling in a single mouse oocyte.

Jiang Yi-Rong YR Zhu Le L Cao Lan-Rui LR Wu Qiong Q Chen Jian-Bo JB Wang Yu Y Wu Jie J Zhang Tian-Yu TY Wang Zhao-Lun ZL Guan Zhi-Ying ZY Xu Qin-Qin QQ Fan Qian-Xi QX Shi Shao-Wen SW Wang Hui-Feng HF Pan Jian-Zhang JZ Fu Xu-Dong XD Wang Yongcheng Y Fang Qun Q

Cell reports 20231116 11

Although single-cell multi-omics technologies are undergoing rapid development, simultaneous transcriptome and proteome analysis of a single-cell individual still faces great challenges. Here, we developed a single-cell simultaneous transcriptome and proteome (scSTAP) analysis platform based on microfluidics, high-throughput sequencing, and mass spectrometry technology to achieve deep and joint quantitative analysis of transcriptome and proteome at the single-cell level, providing an important r ...[more]

PMID: 37976159

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