TAK1 is an essential kinase for STING trafficking

ABSTRACT: STING-mediated activation of TAK1 at the ER, which in turn induces STING phosphorylation and initiates STEEP-mediated STING trafficking. These findings shed light on an early signaling event in the regulation of STING exit from ER.

ORGANISM(S): Homo Sapiens Mus Musculus

SUBMITTER: Haipeng Liu  

PROVIDER: PXD045096 | iProX | Tue Sep 05 00:00:00 BST 2023

REPOSITORIES: iProX