Dataset Information

Non-invasive biomarker discovery in hereditary angioedema

ABSTRACT: Hereditary angioedema (HAE) is a rare and potentially life-threatening disease. The pathogenesis of HAE is not well understood. Moreover, non-invasive disease biomarkers are strongly needed for early diagnosis and clinical management of HAE.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jianqiang Wu

PROVIDER: PXD045435 | iProX | Mon Sep 18 00:00:00 BST 2023

REPOSITORIES: iProX

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Publications

Validation of diagnostic and predictive biomarkers for hereditary angioedema via plasma N-glycomics.

Zhang Zejian Z Wang Xue X Gu Jianqing J Wu Jianqiang J Cao Yang Y Xu Yingyang Y Li Lisha L Guan Kai K Liu Peng P Yin Jia J Zhi Yuxiang Y Zhang Shuyang S

Clinical and translational allergy 20211201 10

<h4>Background</h4>Hereditary angioedema (HAE) is a rare disease with heterogeneous clinical symptoms. It is vitally important to predict whether an HAE patient will develop severe symptoms in clinical practice, but there are currently no predictive biomarkers for HAE stratification. Plasma N-glycomes are disease-specific and have great potential for the discovery of non-invasive biomarkers. In this study, we profiled the plasma N-glycome of HAE patients from two independent cohorts to identify ...[more]

PMID: 34962719

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Dataset Information

Non-invasive biomarker discovery in hereditary angioedema

Publications

Validation of diagnostic and predictive biomarkers for hereditary angioedema via plasma N-glycomics.

Similar Datasets

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