Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: Mingliang Ye
PROVIDER: PXD045630 | iProX | Mon Sep 25 00:00:00 BST 2023
REPOSITORIES: iProX
Fang Zheng Z Qin Hongqiang H Mao Jiawei J Wang Zhongyu Z Zhang Na N Wang Yan Y Liu Luyao L Nie Yongzhan Y Dong Mingming M Ye Mingliang M
Nature communications 20220407 1
Glycopeptides with unusual glycans or poor peptide backbone fragmentation in tandem mass spectrometry are unaccounted for in typical site-specific glycoproteomics analysis and thus remain unidentified. Here, we develop a glycoproteomics tool, Glyco-Decipher, to address these issues. Glyco-Decipher conducts glycan database-independent peptide matching and exploits the fragmentation pattern of shared peptide backbones in glycopeptides to improve the spectrum interpretation. We benchmark Glyco-Deci ...[more]