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Platelet-rich plasma in young and elderly human exhibit a different proteomic profile

ABSTRACT: we prepared platelet-rich plasma from the blood of 6 young volunteers and 6 elderly volunteers, respectively, and removed 95% of high-abundance proteins, followed by mass spectrometry analysis.

ORGANISM(S): Homo Sapiens

SUBMITTER: Kunfu Ouyang

PROVIDER: PXD045750 | iProX | Thu Sep 28 00:00:00 BST 2023

REPOSITORIES: iProX

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Platelet-Rich Plasma in Young and Elderly Humans Exhibits a Different Proteomic Profile.

Jiang Zhitong Z Huang Can C Guo Erliang E Zhu Xiangbin X Li Na N Huang Yu Y Wang Peihe P Shan Hui H Yin Yuxin Y Wang Hong H Huang Lei L Han Zhen Z Ouyang Kunfu K Sun Lu L

Journal of proteome research 20240415 5

As people age, their ability to resist injury and repair damage decreases significantly. Platelet-rich plasma (PRP) has demonstrated diverse therapeutic effects on tissue repair. However, the inconsistency of patient outcomes poses a challenge to the practical application of PRP in clinical practice. Furthermore, a comprehensive understanding of the specific impact of aging on PRP requires a systematic investigation. We derived PRP from 6 young volunteers and 6 elderly volunteers, respectively. ...[more]

PMID: 38619924

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