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Comparative proteome analysis revealed the differences in response to both M.tb and Mb infection of bovine alveolar macrophages

ABSTRACT: Comparative proteome analysis revealed the differences in response to both M.tb and Mb infection of bovine alveolar macrophages

ORGANISM(S): Bos Taurus

SUBMITTER: Yong Li

PROVIDER: PXD045955 | iProX | Sat Oct 07 00:00:00 BST 2023

REPOSITORIES: iProX

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Comparative proteome analysis revealed the differences in response to both Mycobacterium tuberculosis and Mycobacterium bovis infection of bovine alveolar macrophages.

Cai Yurong Y Gao Weifeng W Wang Pu P Zhang Gang G Wang Xiaoping X Jiang Lingling L Zeng Jin J Wang Yujiong Y Wu Zhiwei Z Li Yong Y

Frontiers in cellular and infection microbiology 20231101

Tuberculosis (TB), attributed to the Mycobacterium tuberculosis complex, is one of the most serious zoonotic diseases worldwide. Nevertheless, the host mechanisms preferentially leveraged by Mycobacterium remain unclear. After infection, both Mycobacterium tuberculosis (MTB) and Mycobacterium bovis (MB) bacteria exhibit intimate interactions with host alveolar macrophages; however, the specific mechanisms underlying these macrophage responses remain ambiguous. In our study, ...[more]

PMID: 38029268

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