Screening for the transcriptional factors interacted with Id1 in RAW264.7 cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: 
Fang Hua
PROVIDER: PXD046173 | iProX | Tue Oct 17 00:00:00 BST 2023
REPOSITORIES: iProX
Publications
ID1 expressing macrophages support cancer cell stemness and limit CD8<sup>+</sup> T cell infiltration in colorectal cancer.
Shang Shuang S Yang Chen C Chen Fei F Xiang Ren-Shen RS Zhang Huan H Dai Shu-Yuan SY Liu Jing J Lv Xiao-Xi XX Zhang Cheng C Liu Xiao-Tong XT Zhang Qi Q Lu Shuai-Bing SB Song Jia-Wei JW Yu Jiao-Jiao JJ Zhou Ji-Chao JC Zhang Xiao-Wei XW Cui Bing B Li Ping-Ping PP Zhu Sheng-Tao ST Zhang Hai-Zeng HZ Hua Fang F
Nature communications 20231123 1
Elimination of cancer stem cells (CSCs) and reinvigoration of antitumor immunity remain unmet challenges for cancer therapy. Tumor-associated macrophages (TAMs) constitute the prominant population of immune cells in tumor tissues, contributing to the formation of CSC niches and a suppressive immune microenvironment. Here, we report that high expression of inhibitor of differentiation 1 (ID1) in TAMs correlates with poor outcome in patients with colorectal cancer (CRC). ID1 expressing macrophages ...[more]
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