Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: Ruijun Tian
PROVIDER: PXD046518 | iProX | Tue Oct 31 00:00:00 GMT 2023
REPOSITORIES: iProX
Chen Jin J Yang Lijun L Li Chang C Zhang Luobin L Gao Weina W Xu Ruilian R Tian Ruijun R
Molecular & cellular proteomics : MCP 20231010 11
Carcinoembryonic antigen (CEA) of human plasma is a biomarker of many cancer diseases, and its N-glycosylation accounts for 60% of molecular mass. It is highly desirable to characterize its glycoforms for providing additional dimension of features to increase its performance in prognosis and diagnosis of cancers. However, to systematically characterize its site-specific glycosylation is challenging because of its low abundance. Here, we developed a highly sensitive strategy for in-depth glycosyl ...[more]