An E3 ligase TRIM1 promotes colorectal cancer progression via K63-linked ubiquitination and activation of HIF1α

ABSTRACT: We determined the binding and ubiquitination of HIF1a by an E3 ligase TRIM1. IP experiments were performed from SW480 cells and Ms files were acquired on Q Exactive mass spectrometer. We analysed the differences of protein abundance, comparing the normalized intensity on distinct proteins from different groups.

ORGANISM(S): Homo Sapiens

SUBMITTER: Kun Meng  

PROVIDER: PXD046557 | iProX | Thu Feb 22 00:00:00 GMT 2024

REPOSITORIES: iProX