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The proteins interacting with MPXV-F3L protein identified by LC-MS

ABSTRACT: Monkeypox virus (MPXV) is a double-stranded DNA virus that poses a significant threat to global public health security.In this project, we present data on the proteomics of F3L-transfected HEK293T cells, to identify the proteins interacting with MPXV-F3L protein by LC-MS,aiming to enhance our comprehension of F3L.

ORGANISM(S): Homo Sapiens

SUBMITTER: Lingbao Kong

PROVIDER: PXD047921 | iProX | Mon Dec 18 00:00:00 GMT 2023

REPOSITORIES: iProX

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Transcriptome and proteomic analysis of mpox virus F3L-expressing cells.

Wang Yihao Y Zhang Junzhe J Li Mingzhi M Jia Mengle M Yang Lingdi L Wang Ting T Wang Yu Y Kang Lumei L Li Meifeng M Kong Lingbao L

Frontiers in cellular and infection microbiology 20240213

<h4>Background</h4>Monkeypox or mpox virus (mpox) is a double-stranded DNA virus that poses a significant threat to global public health security. The F3 protein, encoded by mpox, is an apoenzyme believed to possess a double-stranded RNA-binding domain (dsRBD). However, limited research has been conducted on its function. In this study, we present data on the transcriptomics and proteomics of F3L-transfected HEK293T cells, aiming to enhance our comprehension of F3L.<h4>Methods</h4>The gene expre ...[more]

PMID: 38415010

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