Dataset Information
Chronic Stress Induced and Tumor Derived SP1+ exosomes Polarizing IL-1β+ Neutrophils to Increase Lung Metastasis of Breast Cancer
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: 
Jian Huang
PROVIDER: PXD048125 | iProX | Tue Dec 26 00:00:00 GMT 2023
REPOSITORIES: iProX
Publications
Chronic Stress-Induced and Tumor Derived SP1<sup>+</sup> Exosomes Polarizing IL-1β<sup>+</sup> Neutrophils to Increase Lung Metastasis of Breast Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20241204 4
Chronic stress can significantly promote breast cancer progression. When exposed to chronic stress, exosomes released from neural and neuroendocrine cells in the central nervous system are enhanced and modified. However, whether tumor-derived exosomes (TDEs) are influenced by chronic stress and participate in chronic stress-mediated distant metastasis remains unclear. Here, it is shown that chronic stress remarkably facilitates the secretion of TDEs and modifies the contents of exosomes by activ ...[more]
