Proteomics

Dataset Information

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Mouse colon proteomics 4D_DIA sequencing


ABSTRACT: Ulcerative colitis (UC) is a chronic inflammatory bowel disease marked by a distinct pathology that includes superficial ulcerations, inflammatory infiltration, and increased apoptosis of intestinal epithelial cells (IECs) . These features contribute significantly to the disease's progression, with the recurrent inflammation in the colonic mucosa leading to a globally increasing incidence . The enhanced apoptosis of IECs, coupled with inflammation and mucosal ulceration, plays a pivotal role in exacerbating UC and complicating the healing process of the colonic tissue.

ORGANISM(S): Mus Musculus

SUBMITTER: Liangru Zhu  

PROVIDER: PXD049269 | iProX | Tue Feb 06 00:00:00 GMT 2024

REPOSITORIES: iProX

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