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Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis

ABSTRACT: Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis

ORGANISM(S): Homo Sapiens

SUBMITTER: Hongxuan Feng

PROVIDER: PXD050309 | iProX | Mon Mar 04 00:00:00 GMT 2024

REPOSITORIES: iProX

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Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis.

Ma Mian M Cheng Ying Y Hou Xiaoxia X Li Zhisen Z Wang Meixia M Ma Bodun B Cheng Qingzhang Q Ding Zhiliang Z Feng Hongxuan H

Frontiers in neurology 20240322

<h4>Objective</h4>To investigate the serum biomarkers in patients with drug-resistant epilepsy (DRE).<h4>Methods</h4>A total of 9 DRE patients and 9 controls were enrolled. Serum from DRE patients was prospectively collected and analyzed for potential serum biomarkers using TMT18-labeled proteomics. After fine quality control, bioinformatics analysis was conducted to find differentially expressed proteins. Pathway enrichment analysis identified some biological features shared by differential pro ...[more]

PMID: 38585359

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