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Quantitative proteomics revealed novel protein biomarkers to distinguish malignant pleural effusion from benign pleural effusion

ABSTRACT: A four-dimensional independent data acquisition (4D-DIA) proteomic was performed to determine the differentially expressed proteins in pleural effusion samples collected from ung adenocarcinoma MPE, BPE (tuberculosis pleural effusion (TPE) and parapneumonic effusion (PPE)).

ORGANISM(S): Proteinus

SUBMITTER: Xinglin Gao

PROVIDER: PXD050477 | iProX | Fri Mar 08 00:00:00 GMT 2024

REPOSITORIES: iProX

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Quantitative proteomics revealed protein biomarkers to distinguish malignant pleural effusion from benign pleural effusion.

Dong Tingyan T Liang Yueming Y Chen Hui H Li Yanling Y Li Zhiping Z Gao Xinglin X

Journal of proteomics 20240518

To identify protein biomarkers capable of early prediction regarding the distinguishing malignant pleural effusion (MPE) from benign pleural effusion (BPE) in patients with lung disease. A four-dimensional data independent acquisition (4D-DIA) proteomic was performed to determine the differentially expressed proteins in samples from 20 lung adenocarcinoma MPE and 30 BPE. The significantly differential expressed proteins were selected for Gene Ontology (GO) enrichment and Kyoto Encyclopaedia of G ...[more]

PMID: 38768894

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