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COVID-19 infection on human semen quality

ABSTRACT: Compare the proteomic difference after COVID-19 infection.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jialyu Huang

PROVIDER: PXD050512 | iProX | Fri Mar 08 00:00:00 GMT 2024

REPOSITORIES: iProX

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Seminal plasma proteomics of asymptomatic COVID-19 patients reveals disruption of male reproductive function.

Huang Jialyu J Su Yufang Y Wang Jiawei J Fang Zheng Z Zhang Yiwei Y Chen Hong H Wan Xinxia X Xiong Yuanhuan Y Song Ning N Chen Houyang H Wu Xingwu X

BMC genomics 20250321 1

<h4>Background</h4>A considerable proportion of males suffer from asymptomatic SARS-CoV-2 infection, while the effect on reproductive function and underlying pathomechanisms remain unclear.<h4>Results</h4>The total sperm count decreased evidently after asymptomatic infection, yet all semen samples were tested to be SARS-CoV-2 RNA negative. Through label‑free quantitative proteomic profiling, a total of 733 proteins were further identified in seminal plasma from 11 COVID-19 patients and seven uni ...[more]

PMID: 40119256

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